The study was carried out to determine the perceived relational support as determinant of entrepreneurial readiness of business education students in Colleges of Education in South-West, Nigeria. To achieve the objectives of the study, 2 research questions were raised and answered while two null hypotheses were tested at 0.05 level of significance. The study adopted correlational research design. The population for the study consisted of 6,929 business education students. Proportional sampling technique was used to obtain a sample of 693 respondents. The questionnaire was face and content validated by 3 experts from the Department of Business and Entrepreneurship Education, Kwara State University, Malete. Cronbach Alpha method was adopted to ensure reliability of the instrument with the coefficient of r =0.96. The questionnaire was administered on 693 respondents out of which 673 were retrieved from the respondents indicating 97% level of retrieval. Mean and standard deviation were used to answer data related to research questions while t-test and Pearson Product Moment Correlation were used to test the null hypotheses formulated. The findings of the study revealed that business education students’ perceived relational support is moderately high in relation to their entrepreneurial readiness and relationship was found between business education students’ perceived relational support and entrepreneurial readiness. Based on the findings, it was recommended among others that students should develop good bonds within the family setting and at the same time government should re-orientate parents to assist the young graduates when the need arises.